1963 Jan 18:158–165.Bohr model of all Elements is mentioned in the chart below. Stopped-flow measurements of CO and O2 uptake by hemoglobin in sheep erythrocytes. The effect of temperature on the reaction of carbon monoxide with oxygenated haemoglobin. The kinetics of the reaction of carbon monoxide with fully oxygenated haemoglobin in solution and erythrocytes. The determination of the individual equilibrium constants of the four intermediate reactions between oxygen and sheep haemoglobin.
The equilibrium between carbon monoxide and sheep haemoglobin at very high percentage saturations. The specific influence of carbon dioxide and carbamate compounds on the buffer power and Bohr effects in human haemoglobin solutions. The Bohr effect and combination with organic phosphates.Stereochemistry of cooperative effects in haemoglobin. The carbamino reactions of oxygenated and deoxygenated haemoglobin. The reactions catalysed by carbonic anhydrase. Thermal studies of the rates of the reactions of carbon dioxide in concentrated haemoglobin solutions and in red blood cells. The carbon monoxide dissociation curve of human blood. Characterization of intermediate states in the ligation of hemoglobin. The kinetics of dissociation of the first ligand molecule from fully saturated carboxyhaemoglobin and nitric oxide haemoglobin in sheep blood solutions. The kinetics of dissociation of the first oxygen molecule from fully saturated oxyhaemoglobin in sheep blood solutions. The laws of combination of haemoglobin with carbon monoxide and oxygen.
Partition of carbon monoxide and oxygen between air and whole blood of rats, dogs and men as affected by plasma pH. Links to PubMed are also available for Selected References. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page.
CARBON BOHR MODEL FULL
Full textįull text is available as a scanned copy of the original print version. Each intermediatory complex has different rate constants for CO and O2.
An analysis of these results suggest that the Bohr effect, of pH and PCO2, is a dynamic equilibrium between four stable tertiary states of each of the alpha and beta chains. In both situations the value of r was found to have a miximum, for a given PO2/PCO ratio and CO cencentration, at pH 7.2. Measurements were made of the rate of the reaction when the pH was varied, with constant or varying PCO2. The relationship of the reciprocal of r to the ratio PO2/PCO is nonlinear, and a different curve is obtained at each CO concentration. In the presence of CO2, the reaction proceeds by a unimolecular dissociation, with a rate constant r. The rate at which CO displaces O2 from its combination with haemoglobin in solution, has been measured spectrophotometrically, using a rapid-mixing stopped-flow technique.
0 kommentar(er)
